Package guidemaker
GuideMaker: Software to design gRNAs pools in non-model genomes and CRISPR-Cas systems.
Expand source code
"""GuideMaker: Software to design gRNAs pools in non-model genomes and CRISPR-Cas systems."""
import pkg_resources
from ._version import get_versions
from .core import *
from .cli import *
from .definitions import *
from .cfd_score_calculator import *
from .doench_predict import *
from .doench_featurization import *
CONFIG_PATH = pkg_resources.resource_filename('guidemaker', 'data/config_default.yaml')
APP_PARAMETER_IMG = pkg_resources.resource_filename('guidemaker', 'data/parameters.png')
APP_EXPERIMENT_FILE = pkg_resources.resource_filename('guidemaker', 'data/PooledCRISPRExperiments.md')
WEB_APP = pkg_resources.resource_filename('guidemaker', 'data/app.py')
__all__ = ["core", "cli", "definitions", "doench_featurization", "doench_predict", "cfd_score_calculator"]
__version__ = get_versions()['version']
del get_versions
Sub-modules
guidemaker.cfd_score_calculator
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cfd_score_calculator.py This is a modified version of the CDF score calculator in Doench et al. (2016) for use in Guidemaker (https://guidemaker.org) …
guidemaker.cli
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GuideMaker: The command line interface A command line Software to design gRNAs pools in non-model genomes and CRISPR-Cas systems
guidemaker.core
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Core classes and functions for GuideMaker.
guidemaker.data
guidemaker.definitions
guidemaker.doench_featurization
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doench_featurization.py. Simplified feature extraction to run the model 'V3_model_nopos' from Doench et al. 2016 for on-target scoring …
guidemaker.doench_predict
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doench_predict.py. Simplified module to run the model 'V3_model_nopos' from Doench et al. 2016 for on-target scoring …